Novel Laboratory Tests in Assessment of Liver Function in Acute and Chronic Liver Diseases

liver fibrosis in patients with chronic liver diseases: are laboratory tests useful to diagnosis?

Liver fibrosis in patients with chronic liver diseases: are laboratory tests useful to diagnosis?

The article published in Hepatitis Monthy on noninvasive assessment of liver fibrosis with the aspartate transaminasis to platelet ratio index (APRI) in patients with chronic liver disease by Yilmaz et al. (1), is interesting and very useful to permit a diagnosis and staging of fibrosis, although this index does not seem to have a high sensitivity and specificity. In recent years, efforts have ...

A review on laboratory liver function tests

Laboratory liver tests are broadly defined as tests useful in the evaluation and treatment of patients with hepatic dysfunction. The liver carries out metabolism of carbohydrate, protein and fats. Some of the enzymes and the end products of the metabolic pathway which are very sensitive for the abnormality occurred may be considered as biochemical marker of liver dysfunction. Some of the bioche...

Severity Assessment of Chronic Liver Disease in Children

Introduction: Chronic liver disease and cirrhosis are the most important causes of growth failure, morbidity and mortality in children. Cirrhosis consists of a variety of congenital, genetic, metabolic, and infectious causes in children. Models for predicting of chronic liver disease severity, survival, and transplantation are useful for decision-making as well as medical interventions. The mo...

Alterations in liver and thyroid function tests in patients with lead poisoning

Background: Exposure to lead, damages vital organs and is now a global concern. Toxic effects of lead on the liver and thyroid gland have been mentioned previously, sometimes with conflicting results. Therefore, the present study aimed to assess changes in liver and thyroid function tests in patients with lead poisoning. Methods: This case-control study was performed on 100 patients with clini...